# Neurotoxin learning maps — taxonomy · equivalence · name-decode · mnemonics

> Learning aid (renders in Obsidian). Units are NOT interchangeable 1:1. Verify vs IFU.
>
> **Canonical mnemonics → `mnemonics.md`** · recall deck (spaced repetition) → `recall.md`. The §4 hooks below are the in-context subset.

## 0. Master idea
**All botulinum toxins = same molecule (BoNT-A mostly).** They differ by: **units** (brand-specific,
never 1:1), complexing protein, onset/duration/diffusion, formulation (powder vs liquid), origin.

```mermaid
mindmap
  root((Botulinum toxin))
    Serotype
      A almost all
      B Myobloc / Neurobloc
    By INN
      onabotulinumtoxinA = Botox
      abobotulinumtoxinA = Dysport
      incobotulinumtoxinA = Xeomin / Bocouture
      prabotulinumtoxinA = Jeuveau / Nuceiva
      daxibotulinumtoxinA = Daxxify
      letibotulinumtoxinA = Letybo
      relabotulinumtoxinA = Relfydess
    Formulation
      Powder reconstitute
      Ready-to-use liquid Alluzience, Innotox, Relfydess
    Complexing protein
      With Botox, Dysport
      Naked / none Xeomin
    Origin
      Western
      Korean Nabota, Botulax, Coretox, Meditoxin
      Chinese Hengli
```

## 1. Units & conversion (THE key concept — never 1:1)
| From → to | Ratio (approx) |
|---|---|
| Botox : Dysport | 1 : 2.5–3 |
| Botox : Xeomin | ~1 : 1 |
| Botox : Jeuveau | ~1 : 1 |
| Botox : Daxxify | ~1 : 1 (longer duration, not more units) |
| A : B (Myobloc) | 1 : ~50 (very different) |

## 2. Cross-brand equivalence (same drug, different market names)
| Concept | US / generic | EU aesthetic name | Notes |
|---|---|---|---|
| onaA | Botox | Vistabel / Vistabex | original, complexing protein |
| aboA | Dysport | Azzalure · Alluzience (liquid) | ~2.5× units, more spread |
| incoA | Xeomin | Bocouture | "naked", no complexing protein |
| praA | Jeuveau | Nuceiva | "newtox" |
| daxiA | Daxxify | — | ~6-month duration (peptide) |
| letiA | Letybo | Letybo | Korean (Hugel) |
| relaA | Relfydess | — | Galderma liquid RTU (PEARL), day-1 onset; EU/UK, US pending |

## 3. Name-decode
```mermaid
mindmap
  root((Names))
    Botox = BOtulinum TOXin
    Dysport = dystonia + Ipsen
    Xeomin = Xeo = naked no protein
    Bocouture = Botulinum + couture EU Xeomin
    Vistabel = vista/look EU Botox
    Azzalure = allure EU Dysport
    Jeuveau = nouveau = new = newtox
    Daxxify = lasts peptide ~6mo
    Alluzience = allure + science liquid Dysport
    Innotox = innovative liquid Medytox
```

## 4. Mnemonics (hooks)
- **Botox** = BOtulinum TOXin (the original benchmark).
- **Dysport** = think **×2.5 units** + more diffusion (bigger areas / larger muscles).
- **Xeomin** = "**Xeo = naked**" → no complexing protein → 1:1 with Botox; good if antibody resistance.
- **Bocouture / Azzalure / Vistabel** = the pretty **EU aesthetic names** (Xeomin / Dysport / Botox).
- **Jeuveau** = nou**veau** = "**newtox**", ~1:1 with Botox.
- **Daxxify** = "**Dax = dura**" → ~6-month duration (peptide, not more units).
- **Alluzience / Innotox / Relfydess** = **liquid, ready-to-use** (no reconstitution).
- **Relfydess** = Galderma's **liquid** RTU (relabotulinumtoxinA, PEARL tech), day-1 onset, ~6 mo; EU/UK/Asia/Australia, US pending.
- **Serotype B (Myobloc)** = totally different units (~50×), rarely aesthetic.

## 5. In the xlsx
`neurotoxin-map.xlsx` → **Catalogue** default-sorts by **INN** (groups the drug families). Filter by
Brand / Region / Serotype. See the **Unit Equivalence** + **Reconstitution / Dilution** tabs.


<!-- panorama-tiein -->
## New — 2026 panorama tie-in

> Cross-catalog hub: `panorama.md`. CIMA Spain 15 SKUs (sheet 11): 7 aesthetic / 8 therapeutic. Units: IU-type 4 U/0.1 mL vs Speywood 20 U/0.1 mL. Dose-per-point as volume on a 1 mL syringe: sheets 04 + 12.