--- tags: [flashcards, learning-aid] --- # Recall deck — active recall for the whole atlas · repaso espaciado > **Spaced-repetition deck (Obsidian "Spaced Repetition" plugin).** Cover the answer, recall, check. > Format: `Question::Answer` (single-line) and `==cloze==` (renders as highlight; each blank = one card). > Every fact traces to the maps / `mnemonics.md` — **nothing invented. Verify vs IFU/FT/SmPC before clinical use.** > Bilingual **EN · ES**. To use: install the *Spaced Repetition* plugin → this note is tagged `#flashcards`. > Anki export later = replace `::` with a tab (Front/Back). Cloze cards are Obsidian-native. --- #flashcards/toxins Botulinum toxin — what actually differs between brands (never 1:1)?::The **units** (brand-specific), + complexing protein, onset/duration/diffusion, formulation. Same molecule (BoNT-A). The two toxin unit families?::**IU-type** (ona/inco/leti/prabo ≈ 1:1) and **Speywood** (Dysport/Azzalure/Alluzience). *Un número para el club; Dysport habla Speywood.* Standard concentration of an **IU-type** toxin (Botox/Xeomin/Letybo/Jeuveau)?::==4 U / 0.1 mL== Standard concentration of a **Speywood** toxin (Dysport/Azzalure/Alluzience)?::==20 U / 0.1 mL== — 5× more concentrated than IU-type. Botox : Dysport unit conversion ratio?::~ ==1 : 2.5–3== (Dysport needs ~2.5–3× the number). The "Speywood trap" in one line?::**5× stronger per drop → inject half the drops.** Same *volume* as Botox = 5× the dose. A Speywood glabella point is what volume vs an IU-type point?::**Half** — ==0.05 mL== (10 Speywood U) vs 0.1 mL (4 IU-type U), same 5 points. On a 1 mL U-100 syringe, what does each mark represent?::==0.01 mL== of **volume** — NOT toxin units. At 4 U/0.1 mL, which syringe mark = one IU-type point?::The **"10" mark** (0.1 mL). A Speywood point = the "5" mark (0.05 mL). Glabella reference dose — IU-type / Speywood / Daxxify?::==20 U== / ==50 Speywood U== / ==40 DU==. Xeomin's distinguishing feature ("Xeo = naked")?::**No complexing protein** → ~1:1 with Botox; useful in antibody resistance. Daxxify — what's different?::**Own units (DU)** + **~6-month duration** (peptide). Not more units — longer *dura*. No validated conversion. Relfydess vs Alluzience — both Galderma liquids, how do they differ?::**Relfydess** = relaA, **own units** (10 U/0.1 mL). **Alluzience** = aboA, **Speywood** (20 U/0.1 mL). *ALLuzience = ALLied to Dysport.* Type B (Myobloc/Neurobloc) vs type A conversion?::**Never convert** (~50× different); not for aesthetics; low pH stings. The EU-aesthetic names for Botox / Xeomin / Dysport?::**Vistabel** / **Bocouture** / **Azzalure**. Crow's feet dose (IU-type)?::==12 U== per side over ==3 points== (very superficial / intradermal). Forehead (frontalis) dose (IU-type)?::==6–15 U==, ≥2 cm above the brow, over 4–8 points. Masseter dose (IU-type)?::==20–40 U== per side; often concentrated 8 U/0.1 mL (100 U + 1.25 mL). Lip flip — dose and hard cap?::2–4 U total; **cap ~4–6 U total** or risk oral incompetence. Perioral dose shape in one peg?::**"Small mouth, big jaw."** Perioral = single-digit U; masseter = the biggest. Glabella danger — drift too low/lateral hits what → what complication?::**Levator palpebrae → eyelid ptosis.** Stay high, medial to mid-pupil, ==≥1 cm above the orbital rim==. Why never treat the frontalis without the glabella?::Unopposed depressors → **brow drop**. (Heavy lateral dose → **Spock/Mephisto brow**.) Crow's feet danger — too anterior/low hits what?::**Zygomaticus → lip droop / asymmetric smile.** Stay lateral to the rim, ≥1 cm from the canthus. Masseter danger — too high/anterior/superficial?::**Risorius/zygomaticus → asymmetric smile**; too superficial → **paradoxical bulging.** Stay low & posterior, to muscle. Platysmal band danger?::Deep/medial near the larynx → **dysphagia, neck weakness.** Pinch the band, stay subcutaneous, respect caps. The meta-rule for tox complications?::**Right muscle · right depth · right dose.** Almost every complication = drift to the wrong muscle. Reconstitution diluent for toxins?::**Preservative-free 0.9% NaCl**, swirl (don't shake), use within the label window. --- #flashcards/fillers The filler rheology ladder T1→T6 in six words?::**Skin · Soft · Lines · Cheeks · Bones · Body** · *Piel · Suave · Surcos · Pómulos · Hueso · Cuerpo.* As the tier number rises (T1→T6), what happens to depth and G'?::**Deeper + stiffer + more structural.** Bigger number/letter/"max" suffix = deeper. Crosslink tech by house — Restylane / Juvéderm / Belotero?::Restylane = **NASHA + OBT/XpresHAn**; Juvéderm = **Vycross**; Belotero = **CPM**. Crosslink tech by house — Teoxane / Stylage / Neauvia?::Teoxane = **RHA**; Stylage = **IPN + mannitol**; Neauvia = **PEG** (more hyaluronidase-resistant, still HA). Voluma vs Volux?::**Voluma = volUMe → cheek (T4)**; **Volux = luxe/max → jaw/chin (T5)**. Redensity I vs II?::**I = one skin** (meso, superficial). **II = tear trough**, placed **DEEP** despite low G'. Defyne vs Refyne (Restylane)?::**Defyne = Deep/Dynamic** (stronger, folds); **Refyne = Refine/soft** (lighter, fine lines). How do Juvéderm names encode their target?::By suffix: Vol**ux**=jaw, Vol**uma**=cheek, Vol**bella**=lips, Vol**ift**=midface, Vol**ite**=skin. How does Teoxane's RHA line encode depth?::By **number**: RHA **1→4 = skin→deep**. (RHA = Resilient Hyaluronic Acid.) How does Stylage encode depth?::By **letter** = t-shirt sizes: S < M < L < XL < XXL (+ antioxidant mannitol). Which structural (T5) options are NOT reversible?::The biostimulators — **Radiesse (CaHA), Ellansé (PCL), HArmonyCa** (CaHA part). Only the HA fillers reverse. --- #flashcards/biostimulators Biostimulators — mechanism vs fillers?::They **grow your own collagen** (neocollagenesis) over weeks — not instant volume (except CaHA's immediate lift). Biostimulator safety peg (reversibility)?::**"They burn the bridge."** None are HA → **hyaluronidase useless** → dose conservatively. *Queman el puente.* Ellansé S / M / L / E durations?::==1 / 2 / 3 / 4 years== (letters = years; S ~1–1.5). Ellansé = *élan* = the longest (PCL). Sculptra — chemistry, onset, longevity?::**PLLA**; delayed (no day-1 volume), collagen over months; ~2 yr; 2–3 sessions. *eSCULPt slowly.* Radiesse — chemistry and behaviour?::**CaHA**; **immediate lift + delayed** stimulation; ~1–1.5 yr; 1 session. *RADIant now + later.* HArmonyCa — what makes it a hybrid, and what reverses?::**CaHA + HA + lidocaine.** Only the **HA part** is reversible; the CaHA part is not. Lanluma coding — V vs X?::**V = face, X = body** (X = extra). *luma = light/volume* (PLLA). Profhilo — is it a biostimulator?::**No** — a **bioremodeler** (PRO + *hilo*/thread → spreads, no lumps). Not a true foreign-body-response biostimulator. Biostimulator nodule management?::Triamcinolone ± 5-FU; **PLLA nodule → monopolar RF.** Correct plane + massage protocol prevent them. --- #flashcards/skinboosters What do skinboosters/PN treat?::**Skin quality / regeneration, not volume.** Honesty gradient: hydration < bioremodeling < regeneration. Polynucleotide / PDRN peg?::**"nucleo = DNA repair"** (salmon/trout) — Plinest, Rejuran, Nucleofill, PhilArt. ⚠️ fish allergy. Which HA booster has a real RCT?::**SkinVive** — the only one with a Level II RCT. Clinic "exosomes" — the caveat?::EV-enriched, **not true ISEV exosomes; FDA-warned** → adjunct only. Sunekos / Jalupro — what are they?::**HA + amino acids** → build a collagen/elastin scaffold. --- #flashcards/prp PRP process in one line?::**Draw blood → spin → concentrate platelets → growth factors.** The DEPA 2×2 axes?::**Pure vs Leukocyte × Liquid vs Fibrin.** LR vs LP — where does each go?::**"Rich for tendons, Poor for faces."** LR = leukocyte-rich (ortho/tendon); LP = leukocyte-poor (skin/aesthetic). PRP vs PRF — the key difference?::**PRP** = anticoagulant, fast burst. **PRF** = **no anticoagulant** → fibrin clot → slow, sustained release. Only PRP indication with Class-A aesthetic evidence?::**AGA (androgenetic alopecia).** Rest is B–C. Standardise spin + platelet dose or results are random. Which "closed-system" products are NOT PRP?::**Orthokine (ACS), QREM (cytokine serum), WINT (DKK-1/Wnt).** --- #flashcards/technique Cannula vs needle — trade-off?::**Cannula = blunt/safe** (glides past vessels, less bruise); **needle = sharp/precise** (fine detail). Safest deep plane for boluses?::**Supraperiosteal.** The three vascular danger zones ("blindness triangle")?::**Glabella · nose · tear trough** (Cotofana). The injection safety trio?::**Aspirate · low pressure · small aliquots.** MD Codes vs BeautiPHIcation?::**MD Codes** = de Maio "GPS points" per zone. **BeautiPHIcation** = beauty + **PHI** (golden ratio, Swift) → shape before volume.